Familial chromosome translocation t(3;18)(p21;p11).
نویسندگان
چکیده
منابع مشابه
Familial translocation t(9;16).
We report a female with a deletion of 9p and concomitant duplication of 16q [46,XX,-9,+der(9),t(9;16)(p24;q13)]. Parental chromosome analysis showed a balanced maternal translocation [46,XX,t(9;16)(p24;q13)]. Three other cases of translocations involving chromosomes 9 and 16 have been reported, one of them with identical breakpoints. A review of published reports of deletion 9p and duplication ...
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Balanced chromosome translocations in either parent increase the risk of recurrent miscarriage, unbalanced chromosome rearrangements, congenital malformations, and mental retardation in liveborn offspring. Chromosome aberrations account for at least 50% of fetal losses prior to 15 weeks’ estimated gestation (EGA). Of these, 60% occur secondary to autosomal trisomies (Gardner and Sutherland, 200...
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The finding of an inherited chromosome abnormality (Chl) in several members of a family, including two who had developed chronic lymphocytic leukaemia (Gunz, Fitzgerald, and Adams, i962), led to the suggestion that this abnormality predisposed its carriers to the development of the disease, and that inherited cytogenetic abnormalities of this type might determine some instances of familial leuk...
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ژورنال
عنوان ژورنال: Journal of Medical Genetics
سال: 1981
ISSN: 1468-6244
DOI: 10.1136/jmg.18.2.119